Mass Effect 2 allows players to complete many of its missions in whatever order they see fit, much like in Mass Effect 1.
Spoiler Warning: Please keep in mind that the names of some of the main missions can hint at some of the story beats in Mass Effect 2 All Main Missions in Mass Effect 2 Here’s a list of all of the main missions in Mass Effect 2. Mass Effect 2 contains many side missions that you wouldn’t want to skip, but what if you wanted the quickest route to the end of the game? We’ve got you covered, whether you’re a newcomer or a returning longtime fan.